Malformation rates in children of women with untreated epilepsy: a meta-analysis.

  title={Malformation rates in children of women with untreated epilepsy: a meta-analysis.},
  author={Shawn Fried and Eran Kozer and Irena Nulman and Thomas R Einarson and Gideon Koren},
  journal={Drug safety},
  volume={27 3},
BACKGROUND It is widely quoted that women with epilepsy have a higher than baseline risk for giving birth to a child with malformations, independent of the effects of antiepileptic drugs. OBJECTIVE To determine, based on available evidence, if epilepsy per se represents a teratogenic risk. To systematically review all studies investigating the occurrence of major malformation rates among children of treated or untreated women with epilepsy and non-exposed controls who do not have epilepsy… CONTINUE READING

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