Malevamide D: isolation and structure determination of an isodolastatin H analogue from the marine cyanobacterium Symploca hydnoides.

Abstract

Malevamide D (1), a highly cytotoxic peptide ester, and the known compound curacin D (5) were isolated from a Hawaiian sample of Symploca hydnoides. The structure of 1 was elucidated by spectroscopic analysis including NMR and high-resolution MS/MS. Partial stereochemical assignments of 1 were made by chiral HPLC analysis of acid and base hydrolysates… (More)

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@article{Horgen2002MalevamideDI, title={Malevamide D: isolation and structure determination of an isodolastatin H analogue from the marine cyanobacterium Symploca hydnoides.}, author={F David Horgen and Emily B Kazmierski and Hans E Westenburg and Wesley Y. Yoshida and Paul J. Scheuer}, journal={Journal of natural products}, year={2002}, volume={65 4}, pages={487-91} }