Male-specific expression of Sox9 during gonad development of crocodile and mouse is mediated by alternative splicing of its proline-glutamine-alanine rich domain.

@article{Agrawal2009MalespecificEO,
  title={Male-specific expression of Sox9 during gonad development of crocodile and mouse is mediated by alternative splicing of its proline-glutamine-alanine rich domain.},
  author={Raman Agrawal and Oliver Wessely and Amit Anand and Lalji Singh and Ramesh Kumar Aggarwal},
  journal={The FEBS journal},
  year={2009},
  volume={276 15},
  pages={4184-96}
}
The initial trigger for sexual differentiation is regulated by multiple ways during embryonic development. In vertebrates, chromosome-based mechanisms generally known as genetic sex determination are prevalent; however, some species, such as many reptilians, display temperature-dependent sex determination. The Sry-related transcription factor, Sox9, which is expressed by an evolutionary conserved gene, has been shown to be a key player in the process of sex determination. In the present study… CONTINUE READING

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Highly Influenced

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