Male sex in houseflies is determined by Mdmd, a paralog of the generic splice factor gene CWC22

@article{Sharma2017MaleSI,
  title={Male sex in houseflies is determined by Mdmd, a paralog of the generic splice factor gene CWC22},
  author={Akash Sharma and Svenia D. Heinze and Yanli Wu and Tea Kohlbrenner and I. Morilla and C. Brunner and E. Wimmer and L. van de Zande and M. Robinson and L. Beukeboom and D. Bopp},
  journal={Science},
  year={2017},
  volume={356},
  pages={642 - 645}
}
Disrupting housefly gene reverses sex Sex comes in many forms, even when considered at the molecular level. In different animals, the chromosomes and specific genes that function in sex determination vary widely. As a case in point, the familiar housefly displays a highly variable sex determination system. In this animal, the male determiner (M-factor) instructs male development when it is active, but female development results when it is inactive. Sharma et al. now identify the housefly M… Expand
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