Male sex in houseflies is determined by Mdmd, a paralog of the generic splice factor gene CWC22

Abstract

Across species, animals have diverse sex determination pathways, each consisting of a hierarchical cascade of genes and its associated regulatory mechanism. Houseflies have a distinctive polymorphic sex determination system in which a dominant male determiner, the M-factor, can reside on any of the chromosomes. We identified a gene, Musca domestica male… (More)
DOI: 10.1126/science.aam5498

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