Male reproductive toxicology: comparison of the human to animal models.

  title={Male reproductive toxicology: comparison of the human to animal models.},
  author={Peter K. Working},
  journal={Environmental Health Perspectives},
  pages={37 - 44}
The human male is of relatively low fertility and thus may be at greater risk from reproductive toxicants than are males of the common laboratory animal model species. Lack of knowledge of the physiological differences that contribute to interspecies variation between man and animals can prevent the effective application of animal data to the assessment of human reproductive risk. Evaluation of spermatogenesis from testicular histology, while uncommon, can provide valuable information about… CONTINUE READING
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