Male pattern hair loss: current understanding

  title={Male pattern hair loss: current understanding},
  author={David A. Whiting},
  journal={International Journal of Dermatology},
  • D. Whiting
  • Published 1 August 1998
  • Medicine
  • International Journal of Dermatology
Introduction The most common form of human hair loss is androgenic alopecia (AGA). It affects at least 50% of men by the age of 50 years and 50% of women by the age of 6o years. It is more obvious in men, and often manifests itself a decade earlier in men than in women. Various historic observations have suggested that AGA in men, commonly referred to as male pattern hair loss, results from a combination of heredity and hormones. In 400 

Basic hair transplantation: 2007

Past hair transplantation techniques and studies that have provided the basis for current procedures and new research at how to target successful results are looked at.

Male pattern androgenetic alopecia.

More study is needed with respect to searching for a medication to promote hair growth in androgenic alopecia in women.

[Androgenetic alopecia. Current aspects of a common phenotype].

Clinically, patients present with an alopecia that follows a defined pattern (pattern baldness) and progresses continuously but in varying degrees, and effective therapies are available which can lead to cessation of hair loss.

Androgenetic alopecia in heterozygous carriers of a mutation in the human hairless gene.

The present study reports the first attempt to characterize the phenotype of heterozygous carriers of a mutation in the human hairless gene, and indicates that the presence of a deleterious mutation in one allele of thehairless gene does not affect the pattern of androgenetic hair loss.

Comprehensive Overview and Treatment Update on Hair Loss

An overview of the most common clinical causes of hair loss is presented and updated information on the current available therapeutic options for these disorders is provided.

Male pattern androgenetic alopecia in an Indian context: a perspective study

The present study was an attempt to classify AGA in males with the aim of producing a simple, effective and easily reproducible classification.

Common causes of hair loss – clinical manifestations, trichoscopy and therapy

The first step is to obtain a good history and physical examination, and a prompt diagnosis is very important for the prognosis, while trichoscopy is fundamental for all hair diseases.

Androgenetic alopecia in women.

  • V. Price
  • Medicine, Biology
    The journal of investigative dermatology. Symposium proceedings
  • 2003
The diagnosis of androgenetic alopecia in women is supported by early age of onset, the pattern of increased thinning over the frontal/parietal scalp with greater density over the occipital scalp, retention of the frontal hairline, and the presence of miniaturized hairs.

Management of androgenetic alopecia ★

Androgenetic alopecia (AGA) is the most frequent cause of hair loss affecting up to 50% of men and 40% of women by the age of 50.

Androgenetic alopecia in males: a histopathological and ultrastructural study.

Follicular microinflammation plays an integral role in the pathogenesis of androgenetic alopecia in early cases, and over time, thickening of perifollicular sheath takes place due to increased deposition of collagen, resulting in marked perIFollicular fibrosis, and sometimes ends by complete destruction of the affected follicles in advanced cases.



Androgenetic alopecia: an autosomal dominant disorder.

  • W. Bergfeld
  • Medicine, Biology
    The American journal of medicine
  • 1995

Biology of scalp hair growth.

Hormonal parameters in androgenetic hair loss in the male.

Increased local androgen metabolism and androgen receptor binding in the balding areas confirm the importance of the target organ hair follicle as regulative of androgen influences.

Chronic telogen effluvium: increased scalp hair shedding in middle-aged women.

  • D. Whiting
  • Medicine
    Journal of the American Academy of Dermatology
  • 1996

Male Pattern Baldness: classification and Incidence

A complete understanding of male pattern baldness is essential for consistently good results with hair transplantation, and its use in determining the incidence in 1,000 white adult male subjects is reported.

The transverse anatomy of androgenic alopecia.

Transverse frozen sectioning with toluidine blue staining appeared to be a rapid and reliable tool for studying androgenic alopecia in balding frontal scalp patients.

Steroid 5α-Reductase Deficiency in Man: An Inherited Form of Male Pseudohermaphroditism

In male pseudohermaphrodites born with ambiguity of the external genitalia but with marked virilization at puberty, biochemical evaluation reveals a marked decrease in plasma dihydrotestosterone

The biology of hair.

Male hormone stimulation is prerequisite and an incitant in common baldness

The author concludes that the predisposing factors, including congenital, are ineffective in production of seborrhea, acne vulgaris and premature alopeci in the absence of adequate gonadal hormone substance.