Male mouse recombination maps for each autosome identified by chromosome painting.

  title={Male mouse recombination maps for each autosome identified by chromosome painting.},
  author={Lutz Froenicke and Lorinda K. Anderson and Johannes Wienberg and T Clay Ashley},
  journal={American journal of human genetics},
  volume={71 6},
Linkage maps constructed from genetic analysis of gene order and crossover frequency provide few clues to the basis of genomewide distribution of meiotic recombination, such as chromosome structure, that influences meiotic recombination. To bridge this gap, we have generated the first cytological recombination map that identifies individual autosomes in the male mouse. We prepared meiotic chromosome (synaptonemal complex [SC]) spreads from 110 mouse spermatocytes, identified each autosome by… CONTINUE READING
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