Male infertility and androgen receptor gene mutations: clinical features and identification of seven novel mutations

@article{Ferlin2006MaleIA,
  title={Male infertility and androgen receptor gene mutations: clinical features and identification of seven novel mutations},
  author={A. Ferlin and C. Vinanzi and A. Garolla and R. Selice and D. Zuccarello and C. Cazzadore and C. Foresta},
  journal={Clinical Endocrinology},
  year={2006},
  volume={65}
}
  • A. Ferlin, C. Vinanzi, +4 authors C. Foresta
  • Published 2006
  • Biology, Medicine
  • Clinical Endocrinology
  • Objective  Androgens and a functioning androgen receptor (AR) are essential for development and maintenance of the male phenotype and spermatogenesis. Consistent with this, mutations in the AR gene cause a variety of defects related to androgen insensitivity, ranging from complete feminization to phenotypic males with infertility. The aim of his study was to analyse the prevalence of AR gene mutations in male infertility and to clarify the genotype‐phenotype relation. 
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