Male gender is associated with greater cerebral hypometabolism in frontotemporal dementia: evidence for sex-related cognitive reserve.

@article{Perneczky2007MaleGI,
  title={Male gender is associated with greater cerebral hypometabolism in frontotemporal dementia: evidence for sex-related cognitive reserve.},
  author={Robert Perneczky and Janine Diehl-Schmid and Hans F{\"o}rstl and Alexander Drzezga and Alexander Kurz},
  journal={International journal of geriatric psychiatry},
  year={2007},
  volume={22 11},
  pages={1135-40}
}
BACKGROUND Neuropathological studies suggest that the association between neurodegenerative brain damage and clinical symptoms may be stronger in women than in men; therefore women are more likely to express neurodegeneration as clinical dementia. Furthermore, a recent 18F-FDG PET study explored gender differences in the regional cerebral metabolic rate of glucose (rCMRglc) in patients with Alzheimer's disease and found that, at the same level of severity of cognitive impairment, men showed a… CONTINUE READING
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