Male-female differences in the relative contribution of endothelial vasodilators released by rat tail artery.

@article{Pak2002MalefemaleDI,
  title={Male-female differences in the relative contribution of endothelial vasodilators released by rat tail artery.},
  author={Kirk J. Pak and Greg G. Geary and Sue Piper Duckles and Diana N. Krause},
  journal={Life sciences},
  year={2002},
  volume={71 14},
  pages={1633-42}
}
Several different vasodilator substances can be released by vascular endothelium in response to mechanical stimuli and vasoactive agents. The purpose of this study was to determine whether there is a male-female difference in the relative contributions of nitric oxide (NO) and endothelium-derived hyperpolarizing factor (EDHF) to endothelium-dependent vasodilation. Perfusion pressure was measured in isolated tail arteries from male and female rats. Vasodilators released by mechanical shear… CONTINUE READING
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