Male Microchimerism in the Human Female Brain

@article{Chan2012MaleMI,
  title={Male Microchimerism in the Human Female Brain},
  author={William F. N. Chan and C{\'e}cile Gurnot and Thomas J. Montine and J.A. Sonnen and Katherine A. Guthrie and J. Lee Nelson},
  journal={PLoS ONE},
  year={2012},
  volume={7}
}
In humans, naturally acquired microchimerism has been observed in many tissues and organs. Fetal microchimerism, however, has not been investigated in the human brain. Microchimerism of fetal as well as maternal origin has recently been reported in the mouse brain. In this study, we quantified male DNA in the human female brain as a marker for microchimerism of fetal origin (i.e. acquisition of male DNA by a woman while bearing a male fetus). Targeting the Y-chromosome-specific DYS14 gene, we… 

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