Malaysian Indians are genetically similar to Caucasians: CYP2C9 polymorphism.

  title={Malaysian Indians are genetically similar to Caucasians: CYP2C9 polymorphism.},
  author={Z Zainuddin and Lay Kek Teh and Aisyah Suhaimi and Rusli Ismail},
  journal={Journal of clinical pharmacy and therapeutics},
  volume={31 2},
BACKGROUND CYP2C9 is one of the major drug metabolizing enzymes for many drugs including warfarin, NSAIDs and losartan. It is polymorphic in many populations. Data on the distribution of CYP2C9 and the implication of CYP2C9 polymorphism in the Malaysian population is lacking. Our objectives were therefore to investigate the prevalence of CYP2C9 variants among unrelated healthy volunteers of Malays, Chinese and Indians in Malaysia. METHOD Deoxyribonucleic acid was extracted using standard… CONTINUE READING