Malaria vaccines: the stage we are at

  title={Malaria vaccines: the stage we are at},
  author={Stephen M Todryk and Adrian V S Hill},
  journal={Nature Reviews Microbiology},
With over 1 million deaths annually attributed to malaria, an effective vaccine is an urgently needed intervention. However, the various stages of the malaria parasite lifecycle have differing protective immune mechanisms and clinical endpoints, and usually different, often polymorphic, antigens. Trials using an increasing variety of vaccine platforms and antigens are under way in an attempt to achieve this long-awaited goal. 

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, adjuvanted with AS 02 A , in adults in western Kenya

  • M. E. Polhemus
  • 2007

Phase 1 study of two merozoite surface protein 1 (MSP1(42)) vaccines for Plasmodium falciparum malaria

  • E Malkin
  • PLoS Clin. Trials 2,
  • 2007

Safety and immunogenicity of the Plasmodium falciparum merozoite surface protein-3 long synthetic peptide (MSP3-LSP) malaria vaccine in healthy, semi-immune adult males in Burkina Faso, West Africa

  • Sirima, B S.
  • Vaccine 25,
  • 2007


  • V. A. Stewart
  • 2007

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