Malaria chemotherapy and the "kaleidoscopic" organisation of biomedical research during world war II.


The paper describes the organisational and scientific evolution of the US antimalarial program during World War II. This program screened some 14,000 compounds for antimalarial activity, selected atabrine as the drug of choice in 1943, and later identified chloroquine as a superior compound. It became, arguably, the largest biomedical research effort of the… (More)


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