Malaria and pregnancy: placental cytokine expression and its relationship to intrauterine growth retardation.

@article{Moormann1999MalariaAP,
  title={Malaria and pregnancy: placental cytokine expression and its relationship to intrauterine growth retardation.},
  author={Ann M. Moormann and Amy D. Sullivan and Rosemary A Rochford and Stephen W. Chensue and Paul J. Bock and Themba Nyirenda and Steven Richard Meshnick},
  journal={The Journal of infectious diseases},
  year={1999},
  volume={180 6},
  pages={1987-93}
}
Malaria infections during pregnancy can lead to the delivery of low-birth-weight infants. In this study, cytokine mRNA was measured in placentas from 23 malaria-infected and 21 uninfected primigravid women who had delivered in Mangochi, Malawi, a region with a high rate of transmission of falciparum malaria. Significantly increased expression of interleukin (IL)-1beta, IL-8, and tumor necrosis factor (TNF)-alpha and decreased expression of IL-6 and transforming growth factor-beta1 were found in… CONTINUE READING

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