Malaria Transmission-Blocking Vaccines: Present Status and Future Perspectives

@inproceedings{Doumbo2018MalariaTV,
  title={Malaria Transmission-Blocking Vaccines: Present Status and Future Perspectives},
  author={Ogobara K. Doumbo and Karamoko Niar{\'e} and Sara A Healy and Issaka Sagara and Patrick E Duffy},
  year={2018}
}
Transmission-blocking vaccines (TBVs) utilize Plasmodium sexual stage proteins to induce antibodies that prevent parasites from infecting blood-fed mosquitoes. This type of vaccine, which can be considered a “vaccine of solidarity,” reduces Plasmodium infections within communities without conferring direct protective immunity to the vaccine recipients. The leading TBV candidates have advanced to field clinical trials, where vaccineinduced antibody function has been demonstrated in mosquito… CONTINUE READING
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