Malaria: Origin of the Term “Hypnozoite”

  title={Malaria: Origin of the Term “Hypnozoite”},
  author={Miles B. Markus},
  journal={Journal of the History of Biology},
  • M. Markus
  • Published 2011
  • Biology
  • Journal of the History of Biology
The term “hypnozoite” is derived from the Greek words hypnos (sleep) and zoon (animal). Hypnozoites are dormant forms in the life cycles of certain parasitic protozoa that belong to the Phylum Apicomplexa (Sporozoa) and are best known for their probable association with latency and relapse in human malarial infections caused by Plasmodium ovale and P. vivax. Consequently, the hypnozoite is of great biological and medical significance. This, in turn, makes the origin of the name “hypnozoite” a… 

The hypnozoite concept, with particular reference to malaria

This paper is based on a presentation by the author, as a Life Member of the American Society of Tropical Medicine and Hygiene, to its 59th Annual Meeting in Atlanta, Georgia, USA, 3–7 November 2010, and explains how the name “hypnozoite” is applicable to a latent stage in the life cycle of Plasmodium but to some apparently dormant forms of other kinds of apicomplexan parasites as well.

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  • M. Markus
  • Medicine
    South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde
  • 2011
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Electron microscopy of stages of Isospora felis of the cat in the mesenteric lymph node of the mouse

Stages of Isospora felis of the cat in the mesenteric lymph node of the mouse 25 days after oral inoculation with oocysts, have been described at the ultrastructural level, with a biological function similar to that of the tissue cyst stage of other genera of isosporan coccidia.

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