Malaria: An Update

@article{Basu2017MalariaAU,
  title={Malaria: An Update},
  author={Srikanta Basu and Puneet Kaur Sahi},
  journal={The Indian Journal of Pediatrics},
  year={2017},
  volume={84},
  pages={521-528}
}
  • S. Basu, P. Sahi
  • Published 30 March 2017
  • Medicine
  • The Indian Journal of Pediatrics
India is endemic for malaria with unstable transmission inhibiting the development of immunity and predisposing all age groups to the disease. Children under five are the greatest sufferers with maximum mortality. P. falciparum and P. vivax cause majority of cases. Fever is the cardinal symptom, though no set of signs and symptoms reliably distinguishes malaria from other causes of fever. In all suspected cases parasitological diagnosis should be confirmed before starting the treatment… 
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33 Citations
Highly Influential Citations
1
Background Citations
16

33 Citations

Rationalization of the Laboratory Diagnosis for Good Management of Malaria: Lessons from Transitional Methods
TLDR
A presumptive diagnosis of malaria should be confirmed by the laboratory in all suspected cases in all possible scenarios and for the children under 5 years of age in areas of high transmission, the presumptive diagnosis in certain circumstances could be considered.
Plasmodium falciparum: Multidrug resistance
TLDR
The emergence of multidrug resistance to known antimalarial and the development of new antimalaria to resolve drug resistance condition are summarized.
Molecular diagnosis and therapy for Plasmodium ovale infection of a returned traveler from East Africa.
From Genes to Biomarkers: Understanding the Biology of Malaria Gametocytes and Their Detection
TLDR
The biology of Plasmodium gametocytes, existing tools forgametocyte detection, and features of gametocyte genes are provided to help develop better detection biomarkers and effective strategies to reduce transmission in malaria-endemic countries.
Plasmodium Falciparum Malaria and Severe Dengue Coinfection in a Pulmonary Tuberculosis Patient: Case Report and Literature Review
TLDR
The case of an adult patient with coinfection due to malaria and dengue who is also diagnosed with tuberculosis and required management in the intensive care unit due to multiorgan failure is presented.
Plasmodium falciparum: Experimental and Theoretical Approaches in Last 20 Years
TLDR
This chapter aims to examine the numerous experimental and theoretical works that have been established in the last two decades along with the ongoing methodologies consisting of detailed explanations necessary for the establishment of new targets and drugs.
Descriptive study of malaria cases in the paediatric population in a reference hospital in Valencia, Spain, between 1993 and 2015
Actualización de malaria
TLDR
This pathology occurs in the tropical regions around the world, with high globally rates of incidence, which despite having shown a downward trend in the recent years, it continues to be a public health problem in the endemic regions.
[Descriptive study of malaria cases in the paediatric population in a reference hospital in Valencia, Spain, between 1993 and 2015].
Development of lipid matrix tablets containing a double fixed dose combination of artemisone and lumefantrine
TLDR
Artemisone, an artemisinin derivative, signifies a new class of antimalarial drugs that is an effective blood schizontocide against strains of drug-resistant Plasmodium falciparum malaria and Lumefantrine was chosen as the long acting drug that has poor aqueous solubility, is highly lipophilic and depicts erratic absorption, leading to poor bioavailability.
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