Malaria: An Update

  title={Malaria: An Update},
  author={Srikanta Basu and Puneet Kaur Sahi},
  journal={The Indian Journal of Pediatrics},
  • S. Basu, P. Sahi
  • Published 30 March 2017
  • Medicine
  • The Indian Journal of Pediatrics
India is endemic for malaria with unstable transmission inhibiting the development of immunity and predisposing all age groups to the disease. Children under five are the greatest sufferers with maximum mortality. P. falciparum and P. vivax cause majority of cases. Fever is the cardinal symptom, though no set of signs and symptoms reliably distinguishes malaria from other causes of fever. In all suspected cases parasitological diagnosis should be confirmed before starting the treatment… 
Rationalization of the Laboratory Diagnosis for Good Management of Malaria: Lessons from Transitional Methods
A presumptive diagnosis of malaria should be confirmed by the laboratory in all suspected cases in all possible scenarios and for the children under 5 years of age in areas of high transmission, the presumptive diagnosis in certain circumstances could be considered.
Plasmodium falciparum: Multidrug resistance
The emergence of multidrug resistance to known antimalarial and the development of new antimalaria to resolve drug resistance condition are summarized.
From Genes to Biomarkers: Understanding the Biology of Malaria Gametocytes and Their Detection
The biology of Plasmodium gametocytes, existing tools forgametocyte detection, and features of gametocyte genes are provided to help develop better detection biomarkers and effective strategies to reduce transmission in malaria-endemic countries.
Plasmodium Falciparum Malaria and Severe Dengue Coinfection in a Pulmonary Tuberculosis Patient: Case Report and Literature Review
The case of an adult patient with coinfection due to malaria and dengue who is also diagnosed with tuberculosis and required management in the intensive care unit due to multiorgan failure is presented.
Plasmodium falciparum: Experimental and Theoretical Approaches in Last 20 Years
This chapter aims to examine the numerous experimental and theoretical works that have been established in the last two decades along with the ongoing methodologies consisting of detailed explanations necessary for the establishment of new targets and drugs.
Actualización de malaria
This pathology occurs in the tropical regions around the world, with high globally rates of incidence, which despite having shown a downward trend in the recent years, it continues to be a public health problem in the endemic regions.
Development of lipid matrix tablets containing a double fixed dose combination of artemisone and lumefantrine
Artemisone, an artemisinin derivative, signifies a new class of antimalarial drugs that is an effective blood schizontocide against strains of drug-resistant Plasmodium falciparum malaria and Lumefantrine was chosen as the long acting drug that has poor aqueous solubility, is highly lipophilic and depicts erratic absorption, leading to poor bioavailability.


Malaria in children
Malaria (Plasmodium).
  • R. Mcfee
  • Medicine
    Disease-a-month : DM
  • 2013
Malaria and National Vector Borne Disease Control Programme
The article discusses the recent national drug policy for malaria and the rationale for its use and recommends artemisinin based combination therapy (ACT) as the first-line drugs for P. falciparum malaria in the country.
The Lambaréné-Organ-Dysfunction-Score (LODS), a simple clinical predictor for fatal malaria in African children, provides a sufficiently accurate and rapid identification of children needing either referral or increased attention and has important implications for management guidelines in non endemic countries.
Risk factors for severe disease in adults with falciparum malaria.
The findings of this study demonstrate that ethnicity and parasitemia are important independent risk factors for severe falciparum malaria in adults from malaria-nonendemic countries and that a history of previous clinical malaria significantly reduces the risk of WHO-defined severefalcipareum malaria.
Blackwater Fever in Children, Burundi
Blackwater fever is characterized by acute intravascular hemolysis with hemoglobinuria in patients with Plasmodium falciparum malaria in children receiving multiple quinine treatments.
Proposed criteria for classifying potential dental emergencies in Department of Defense military personnel.
More emphasis should be focused on caries- and surgery-related problems to identify the majority of individuals at high risk for emergencies, and changes in the current system of classification are proposed.
A literature review of dental casualty rates.
The review found the studies to be fairly consistent in that a well-prepared dentally fit force can expect 150 to 200 dental casualties per 1,000 soldiers per year, although maxillofacial cases have remained steady at 25%, dental disease has decreased and endodontic cases have had a corresponding increase.