Maladaptive enlargement of the brachial artery in severe obesity is reversed with weight loss.

@article{Hamburg2010MaladaptiveEO,
  title={Maladaptive enlargement of the brachial artery in severe obesity is reversed with weight loss.},
  author={Naomi M. Hamburg and Melanie M. Mott and Sherman J. Bigornia and Mai-Ann Duess and Matthew A. Kluge and Donald T. Hess and Caroline M Apovian and Joseph A. Vita and Noyan Gokce},
  journal={Vascular medicine},
  year={2010},
  volume={15 3},
  pages={215-22}
}
Maladaptive peripheral arterial remodeling, which leads to large arteries with low shear stress, may be associated with increased cardiovascular risk. We tested the hypothesis that arterial enlargement in severe obesity represents maladaptive remodeling and that weight reduction would reverse this process. We evaluated brachial arterial diameter and flow using ultrasound in 244 severely obese patients (age 44 +/- 11 years, 80% female, body mass index (BMI) 46 +/- 9 kg/m) at baseline and in a… CONTINUE READING