Malabsorption of Vitamin B12 in Pancreatic Insufficiency of the Adult and of the Child

@article{Guant1990MalabsorptionOV,
  title={Malabsorption of Vitamin B12 in Pancreatic Insufficiency of the Adult and of the Child},
  author={J. Gu{\'e}ant and B. Champigneulle and P. Gaucher and J. Nicolas},
  journal={Pancreas},
  year={1990},
  volume={5},
  pages={559–567}
}
Vitamin B12 can bind two carrier proteins in the digestive tract, haptocorrin (R binder) and intrinsic factor, but only its binding to intrinsic factor allows its absorption. A malabsorption of vitamin B12 is observed in about 30% of adult patients with exocrine pancreatic insufficiency, using the Schilling test. None of the hypotheses that have tried to explain this malabsorption are entirely satisfactory. A failure to degrade haptocorrin can prevent the binding of vitamin B., to intrinsic… Expand
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1
2
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...

References

SHOWING 1-10 OF 85 REFERENCES
The Intraluminal Transport of Vitamin B12 and the Exocrine Pancreatic Insufficiency
Pancreatic insufficiency and vitamin B 12 malabsorption.
...
1
2
3
4
5
...