Makorin ring zinc finger protein 1 (MKRN1), a novel poly(A)-binding protein-interacting protein, stimulates translation in nerve cells.

@article{Miroci2012MakorinRZ,
  title={Makorin ring zinc finger protein 1 (MKRN1), a novel poly(A)-binding protein-interacting protein, stimulates translation in nerve cells.},
  author={Hatmone Miroci and Claudia Schob and Stefan Kindler and Janin {\"O}lschl{\"a}ger-Sch{\"u}tt and Susanne Fehr and Tassilo Jungenitz and Stephan W. Schwarzacher and Claudia Bagni and Evita Mohr},
  journal={The Journal of biological chemistry},
  year={2012},
  volume={287 2},
  pages={1322-34}
}
The poly(A)-binding protein (PABP), a key component of different ribonucleoprotein complexes, plays a crucial role in the control of mRNA translation rates, stability, and subcellular targeting. In this study we identify RING zinc finger protein Makorin 1 (MKRN1), a bona fide RNA-binding protein, as a binding partner of PABP that interacts with PABP in an RNA-independent manner. In rat brain, a so far uncharacterized short MKRN1 isoform, MKRN1-short, predominates and is detected in forebrain… CONTINUE READING

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Translational control of synaptic plasticity

J. D. Richter
Biochem. Soc. Trans • 2010

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