Making two movements at once: Impairments of movement, posture, and their integration underlie the adult skilled reaching deficit of neonatally dopamine-depleted rats

@article{Whishaw1994MakingTM,
  title={Making two movements at once: Impairments of movement, posture, and their integration underlie the adult skilled reaching deficit of neonatally dopamine-depleted rats},
  author={Ian Q. Whishaw and Boguslaw P. Gorny and Ly T L Tran-Nguyen and Eddie Casta{\~n}eda and Sergio M. Pellis},
  journal={Behavioural Brain Research},
  year={1994},
  volume={61},
  pages={65-77}
}
Adult rats depleted bilaterally of dopamine in infancy display a profound impairment in skilled forelimb use in reaching for food. This impairment was investigated using end-point measures of reaching success, movement analysis, and kinematic measures. The rats made few successful reaches in either an easy or a difficult reaching test. Their reaches were characterized by many attempts in which trajectories of the limb were irregular and the movements were slow. Their lack of success was related… CONTINUE READING

From This Paper

Topics from this paper.

Citations

Publications citing this paper.
Showing 1-8 of 8 extracted citations

Reduced reach-related modulation of motor thalamus neural activity in a rat model of Parkinson's disease.

The Journal of neuroscience : the official journal of the Society for Neuroscience • 2014
View 5 Excerpts
Highly Influenced