Making alternative splicing decisions during epithelial-to-mesenchymal transition (EMT)

@article{Biamonti2012MakingAS,
  title={Making alternative splicing decisions during epithelial-to-mesenchymal transition (EMT)},
  author={Giuseppe Biamonti and Serena Bonomi and Stefania Gallo and Claudia Ghigna},
  journal={Cellular and Molecular Life Sciences},
  year={2012},
  volume={69},
  pages={2515-2526}
}
Alternative splicing generates multiple mRNAs from a single transcript and is a major contributor to proteomic diversity and to the control of gene expression in complex organisms. Not surprisingly, this post-transcriptional event is tightly regulated in different tissues and developmental stages. An increasing body of evidences supports a causative role of aberrant alternative splicing in cancer. However, very little is known about its impact on cellular processes crucially involved in tumor… CONTINUE READING

3 Figures & Tables

Topics

Statistics

0100200300201320142015201620172018
Citations per Year

497 Citations

Semantic Scholar estimates that this publication has 497 citations based on the available data.

See our FAQ for additional information.