Making a medicine out of MDMA.

@article{Sessa2015MakingAM,
  title={Making a medicine out of MDMA.},
  author={Ben Sessa and David J. Nutt},
  journal={The British journal of psychiatry : the journal of mental science},
  year={2015},
  volume={206 1},
  pages={
          4-6
        }
}
  • B. Sessa, D. Nutt
  • Published 2015
  • Medicine, Psychology, Biology
  • The British journal of psychiatry : the journal of mental science
From its first use 3,4,-methylenedioxymethamphetamine (MDMA) has been recognised as a drug with therapeutic potential. Research on its clinical utility stopped when it entered the recreational drug scene but has slowly resurrected in the past decade. Currently there is enough evidence for MDMA to be removed from its Schedule 1 status of 'no medical use' and moved into Schedule 2 (alongside other misused but useful medicines such as heroin and amphetamine). Such a regulatory move would liberate… 
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Background Citations
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29 Citations

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Dark Classics in Chemical Neuroscience: 3,4-Methylenedioxymethamphetamine.

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The synthesis of MDMA is detailed as well as its pharmacology, metabolism, adverse effects, and potential use in medicine, which discusses its history and why it is perhaps the most important compound for the future of psychedelic science.

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MDMA administration was overall safe in physically and psychiatrically healthy subjects and in a medical setting, however, the risks of MDMA are likely higher in patients with cardiovascular disease and remain to be investigated in Patients with psychiatric disorders.

MDMA and memory, addiction, and depression: dose-effect analysis

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The present dose-ranging study provides further evidence that 3 mg/kg is the threshold for MDMA-induced amnesia and demonstrates that careful selection of MDMA dose is critical.

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  • B. Sessa
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  • 2018

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TLDR
Dr Sessa discusses controversies and describes a UK‐based MDMA/PTSD currently in development, which she describes as an adjunct to post‐trauma psychological therapy.

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