Making Sense of Biostatistics: Clinical Significance

  title={Making Sense of Biostatistics: Clinical Significance},
  author={Jennifer R. Turner},
In the previous two columns, we discussed hypothesis testing and statistical significance. While consideration of statistical significance is informative and necessary in the clinical arena, it is not sufficient. Gardner and Altman (1986) noted that “presenting p-values alone can lead to them being given more merit than they deserve. In particular, there is a tendency to equate statistical significance with medical importance or biological relevance.” Statistical significance must not be… CONTINUE READING


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