Major involvement of mTOR in the PPARγ-induced stimulation of adipose tissue lipid uptake and fat accretion.

@article{Blanchard2012MajorIO,
  title={Major involvement of mTOR in the PPARγ-induced stimulation of adipose tissue lipid uptake and fat accretion.},
  author={Pascal Blanchard and William T Festuccia and Vanessa P. Houde and Philippe St-Pierre and Sophie Br{\^u}l{\'e} and V{\'e}ronique Turcotte and Marie L. Cot{\'e} and Kerstin Bellmann and Andr{\'e} Marette and Yves Deshaies},
  journal={Journal of lipid research},
  year={2012},
  volume={53 6},
  pages={
          1117-25
        }
}
Evidence points to a role of the mammalian target of rapamycin (mTOR) signaling pathway as a regulator of adiposity, yet its involvement as a mediator of the positive actions of peroxisome proliferator-activated receptor (PPAR)γ agonism on lipemia, fat accretion, lipid uptake, and its major determinant lipoprotein lipase (LPL) remains to be elucidated. Herein we evaluated the plasma lipid profile, triacylglycerol (TAG) secretion rates, and adipose tissue LPL-dependent lipid uptake, LPL… CONTINUE READING
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References

Publications referenced by this paper.
SHOWING 1-10 OF 35 REFERENCES

Depot - specifi c effects of the PPAR  agonist rosiglitazone on adipose tissue glucose uptake and metabolism

  • P. G. Blanchard, V. Turcotte, M. Laplante, M. Sariahmetoglu, Y. Deshaies
  • J . Lipid Res .
  • 2009

Tissue - specifi c postprandial clearance is the major determinant of PPAR  - induced triglyceride lowering in the rat

  • G. Soucy, P. G. Blanchard, A. Renaud, J. P. Berger, G. Olivecrona, Y. Deshaies
  • Am . J . Physiol . Regul . Integr . Comp…
  • 2009

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