Major histocompatibility complex genes and susceptibility to systemic lupus erythematosus.

Abstract

Susceptibility to systemic lupus erythematosus is associated with major histocompatibility complex (MHC)--encoded genes. We have used nucleotide sequence analysis to better define the disease-associated MHC alleles. HLA-DR2, DQw1, and especially the rare allele DQ beta 1. AZH confer high relative risk (RR = 14) for lupus nephritis in a Caucasian population… (More)

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Cite this paper

@article{Fronek1990MajorHC, title={Major histocompatibility complex genes and susceptibility to systemic lupus erythematosus.}, author={Z Fronek and Luika A. Timmerman and Chester A. Alper and Beatrice H. Hahn and Kenneth Carekin Kalunian and B. Matija Peterlin and H. O. McDevitt}, journal={Arthritis and rheumatism}, year={1990}, volume={33 10}, pages={1542-53} }