Major histocompatibility complex and tumor necrosis factor-alpha polymorphisms in pigeon breeder's disease.

@article{Camarena2001MajorHC,
  title={Major histocompatibility complex and tumor necrosis factor-alpha polymorphisms in pigeon breeder's disease.},
  author={{\'A}ngel Eduardo Camarena and Armida Ju{\'a}rez and M. Ramos Mej{\'i}a and Andrea Estrada and Guillermo Carrillo and R Falf{\'a}n and Joaqu{\'i}n Z{\'u}{\~n}iga and Carmen Navarro and J. Javier Rainer Granados and Mois{\'e}s Selman},
  journal={American journal of respiratory and critical care medicine},
  year={2001},
  volume={163 7},
  pages={1528-33}
}
Pigeon breeders disease (PBD) is caused by the exposure of a susceptible host to avian antigens. However, genetic factors determining individual predisposition are unknown. In this work, polymorphisms of the major histocompatibility complex (MHC) class II alleles and tumor necrosis factor alpha (TNF-alpha) promoter were evaluated in 44 patients with PBD, 99 healthy unrelated controls (HC), and 50 exposed but asymptomatic subjects (EAS). MHC typing was performed by PCR-specific sequence… CONTINUE READING