Major histocompatibility complex and other allergy-related candidate genes associated with insect bite hypersensitivity in Icelandic horses

@article{Klumplerova2012MajorHC,
  title={Major histocompatibility complex and other allergy-related candidate genes associated with insect bite hypersensitivity in Icelandic horses},
  author={Marie Klumplerova and Leona Vychodilova and O. V. Bobrova and Michaela Cvanov{\'a} and J{\'a}n Futas and Eva J{\'a}nov{\'a} and Mirko Vysko{\vc}il and Irena Vrtkov{\'a} and L Putnov{\'a} and Ladislav Du{\vs}ek and Eliane Marti and Petr Horin},
  journal={Molecular Biology Reports},
  year={2012},
  volume={40},
  pages={3333-3340}
}
Insect bite hypersensitivity (IBH) is an allergic dermatitis of horses caused by bites of insects. IBH is a multifactorial disease with contribution of genetic and environmental factors. Candidate gene association analysis of IBH was performed in a group of 89 Icelandic horses all born in Iceland and imported to Europe. Horses were classified in IBH-affected and non-affected based on clinical signs and history of recurrent dermatitis, and on the results of an in vitro sulfidoleukotriene (sLT… CONTINUE READING

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