Major hepatic trauma: warm ischemic tolerance of the liver after hemorrhagic shock.

@article{Perdrizet2006MajorHT,
  title={Major hepatic trauma: warm ischemic tolerance of the liver after hemorrhagic shock.},
  author={George A. Perdrizet and David L. Giles and Robert J Dring and Suresh K. Agarwal and Khalid Khwaja and Yuan Z. Gao and Michael Geary and Vernon L Cowell and Martin Berman and Robert T Brautigam},
  journal={The Journal of surgical research},
  year={2006},
  volume={136 1},
  pages={70-7}
}
BACKGROUND The management of severe hepatic trauma frequently involves exposing the liver to varying periods of warm ischemia. The ischemic tolerance of the liver, in the setting of hemorrhagic shock (HS) and trauma, is presently unknown. We tested the hypothesis that warm ischemic tolerance of the porcine liver will be decreased following resuscitation from HS. MATERIALS AND METHODS Twenty-three Yorkshire pigs were divided into three groups: 1) hepatic ischemia alone (HI, n = 9); 2… CONTINUE READING