Major gene for percent of oxygen saturation of arterial hemoglobin in Tibetan highlanders.

@article{Beall1994MajorGF,
  title={Major gene for percent of oxygen saturation of arterial hemoglobin in Tibetan highlanders.},
  author={Cynthia M Beall and John Blangero and Sarah Williams-Blangero and Melvyn C. Goldstein},
  journal={American journal of physical anthropology},
  year={1994},
  volume={95 3},
  pages={271-6}
}
This report employs a statistical genetic approach to analyze quantitative oxygen transport variables in a high-altitude (4,850-5,450 m) native Tibetan population and demonstrates the presence of a major gene influencing % O2 saturation of arterial hemoglobin. This result suggests the hypothesis that individuals with the dominant allele for higher % O2 saturation have a selective advantage at high altitude. Studies of the biologically distinctive Himalayan and Andean populations have greatly… CONTINUE READING

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