Major diet-drug interactions affecting the kinetic characteristics and hypolipidaemic properties of statins.

@article{Vaquero2010MajorDI,
  title={Major diet-drug interactions affecting the kinetic characteristics and hypolipidaemic properties of statins.},
  author={M. P. Vaquero and F. J. S{\'a}nchez Muniz and S. Jim{\'e}nez Redondo and P. Prats Oliv{\'a}n and F. J. Higueras and S. Bastida},
  journal={Nutricion hospitalaria},
  year={2010},
  volume={25 2},
  pages={
          193-206
        }
}
Concomitant administration of statins with food may alter statin pharmacokinetics or pharmacodynamics, increasing the risk of adverse reactions such as myopathy or rhabdomyolysis or reducing their pharmacological action. This paper reviews major interactions between statins and dietary compounds. Consumption of pectin or oat bran together with Lovastatin reduces absorption of the drug, while alcohol intake does not appear to affect the efficacy and safety of Fluvastatin treatment. Grapefruit… Expand
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