Major depressive disorder and immunity to varicella-zoster virus in the elderly.

  title={Major depressive disorder and immunity to varicella-zoster virus in the elderly.},
  author={Michael R. Irwin and Myron J. Levin and Carmen Castillo Carrillo and Richard Olmstead and Anne Lucko and Nancy Lang and Michael J. Caulfield and Adriana Weinberg and Ivan Siu Fung Chan and J Bradley St Clair and J. Graham Smith and Rocio D Marchese and Heather MacLeod Williams and Danielle J. Beck and Patricia T McCook and Gary Johnson and Michael N. Oxman},
  journal={Brain, behavior, and immunity},
  volume={25 4},
Major depressive disorder has been associated with activation of inflammatory processes as well as with reductions in innate, adaptive and non-specific immune responses. The objective of this study was to evaluate the association between major depression and a disease-relevant immunologic response, namely varicella-zoster virus (VZV)-specific immunity, in elderly adults. A cross-sectional cohort study was conducted in 104 elderly community dwelling adults ≥ 60years of age who were enrolled in… CONTINUE READING
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