Major decrease in the incidence of trisomy 21 at birth in south Belgium: mass impact of triple test?

@article{Verloes2001MajorDI,
  title={Major decrease in the incidence of trisomy 21 at birth in south Belgium: mass impact of triple test?},
  author={Alain Verloes and Yves Gillerot and Lionel van Maldergem and Roland Schoos and Christian Herens and Mauricette Jamar and Vinciane Dideberg and Sylviane Lesenfants and Lucien Koulischer},
  journal={European Journal of Human Genetics},
  year={2001},
  volume={9},
  pages={1-4}
}
In South Belgium (Wallonia), the ‘triple test’ was introduced in 1990–1991, and is nowadays a widely accepted screening method for assessment of trisomy 21 risk in pregnancy. The ‘triple test’ is not regulated and can be freely performed by any biomedical lab, making epidemiological data unavailable. By contrast, cytogenetic investigations are limited to a few genetic centres, and accurate statistics can be easily built from their files. During the period 1984–1989, a total of 244 trisomy 21 (1… CONTINUE READING
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