Major coagulation disturbances during fractionated plasma separation and adsorption.

  title={Major coagulation disturbances during fractionated plasma separation and adsorption.},
  author={Bj{\"o}rn Meijers and Peter B Verhamme and Frederik Nevens and Marc F Hoylaerts and Bert R M Bammens and Alexander Wilmer and J M M C Arnout and Yves F Ch Vanrenterghem and P Evenepoel},
  journal={American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons},
  volume={7 9},
Fractionated Plasma Separation and Adsorption (FPSA) is a novel nonbiologic detoxification system for the removal of protein-bound solutes. FPSA is used to bridge patients during fulminant liver failure, either to functional recovery or to liver transplantation. Besides liver failure associated protein bound solutes, several important uremic retention solutes share important protein binding. We observed repeated occlusive thrombosis of the arterio-venous conduit during FPSA in hemodialysis (HD… CONTINUE READING