Major Histocompatibility Complex (MHC) Genes and Disease Resistance in Fish

@inproceedings{Yamaguchi2019MajorHC,
  title={Major Histocompatibility Complex (MHC) Genes and Disease Resistance in Fish},
  author={Takuya Yamaguchi and Johannes M Dijkstra},
  booktitle={Cells},
  year={2019}
}
Fascinating about classical major histocompatibility complex (MHC) molecules is their polymorphism. The present study is a review and discussion of the fish MHC situation. The basic pattern of MHC variation in fish is similar to mammals, with MHC class I versus class II, and polymorphic classical versus nonpolymorphic nonclassical. However, in many or all teleost fishes, important differences with mammalian or human MHC were observed: (1) The allelic/haplotype diversification levels of… CONTINUE READING

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