Major Histocompatibility Complex, Class I, B

  title={Major Histocompatibility Complex, Class I, B},
  • Published 2008
Description The genes of the Human Leukocyte Antigen (HLA) system reside on chromosome 6, and code for cellsurface proteins that play a crucial role in the presentation of endogenic peptides to effector cells of the immune system. The HLA Class I protein molecule is a heterodimer, made up of two chains; a heavy one and a light one (beta 2 microglobulin). The HLA-B gene is one of the three HLA Class I heavy chain paralogues. The HLA Class I protein presents peptides from the lumen of the… CONTINUE READING

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