Major Amputation for Irresectable Extremity Melanoma After Failure of Isolated Limb Infusion

@article{Kroon2009MajorAF,
  title={Major Amputation for Irresectable Extremity Melanoma After Failure of Isolated Limb Infusion},
  author={Hidde Maarten Kroon and D-Yin Lin and Peter C. A. Kam and John F Thompson},
  journal={Annals of Surgical Oncology},
  year={2009},
  volume={16},
  pages={1543-1547}
}
Isolated limb infusion (ILI) is an effective, minimally invasive treatment option that delivers high-dose regional chemotherapy to treat metastatic melanoma confined to a limb. In some patients, however, locoregional disease does not respond to the treatment or extensive recurrence occurs so that an amputation may become inevitable. In this study we analyzed indications for and results of amputation in these cases. 14 patients were identified in whom amputation of the affected limb had to be… CONTINUE READING

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