Maitotoxin Is a Potential Selective Activator of the Endogenous Transient Receptor Potential Canonical Type 1 Channel in Xenopus laevis Oocytes

@inproceedings{Flores2017MaitotoxinIA,
  title={Maitotoxin Is a Potential Selective Activator of the Endogenous Transient Receptor Potential Canonical Type 1 Channel in Xenopus laevis Oocytes},
  author={Pedro L. Flores and Emma Rodr{\'i}guez and Estrella Zapata and Roxana Carb{\'o} and Jos{\'e} Mar{\'i}a Far{\'i}as and Mart{\'i}n Romero Mart{\'i}nez},
  booktitle={Marine drugs},
  year={2017}
}
Maitotoxin (MTX) is the most potent marine toxin known to date. It is responsible for a particular human intoxication syndrome called ciguatera fish poisoning (CFP). Several reports indicate that MTX is an activator of non-selective cation channels (NSCC) in different cell types. The molecular identity of these channels is still an unresolved topic, and it has been proposed that the transient receptor potential (TRP) channels are involved in this effect. In Xenopus laevis oocytes, MTX at… CONTINUE READING
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Legislation on the Protection of Animals Used for Scientific Purposes

  • European Commission
  • European Commission Web Site. Available online…
  • 2017
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