• Corpus ID: 6831939

Maitake Extracts and Their Therapeutic Potential - A Review

@inproceedings{Mayell2001MaitakeEA,
  title={Maitake Extracts and Their Therapeutic Potential - A Review},
  author={Mark Mayell},
  year={2001}
}
Maitake (Grifola frondosa) is the Japanese name for an edible fungus with a large fruiting body characterized by overlapping caps. It is a premier culinary as well as medicinal mushroom. Maitake is increasingly being recognized as a potent source of polysaccharide compounds with dramatic health-promoting potential. The most recent development is the MD-fraction, a proprietary maitake extract its Japanese inventors consider to be a notable advance upon the preceding D-fraction. The D-fraction… 

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References

SHOWING 1-10 OF 71 REFERENCES
Effects of Maitake (Grifola frondosa) glucan in HIV-infected patients
TLDR
Results suggest that Maitake D-Fraction had a positive impact in HIV patients, with 85% of respondents reported an increased sense of well-being with regard to various symptoms and secondary diseases caused by HIV.
Antitumor activity exhibited by orally administered extract from fruit body of Grifola frondosa (maitake).
TLDR
D-fraction was found to potentiate the delayed-type hypersensitivity response which is associated with tumor growth suppression and indicates that stimulation of the immune response system triggered by the tumor-bearing state is activated by D- fraction.
MAITAKE D-FRACTION : HEALING AND PREVENTIVE POTENTIAL FOR CANCER
TLDR
Maitake extract D-fraction was investigated to determine its effectiveness not only on the inhibition against tumors already growing, but also on the inhibiting of formation of the secondary focus due to metastasis of tumor cells in lymph and/or blood.
Fractionation and Characterization of Antitumor Polysaccharides from Maitake, Grifola frondosa
Three groups of polysaccharides from the edible mushroom “Maitake,” the cultured fruiting body of Grifola frondosa, were extracted with hot water, 3% NH4-oxalate (100°C), and 5% sodium hydroxide
Potentiation of host-mediated antitumor activity in mice by beta-glucan obtained from Grifola frondosa (maitake).
TLDR
A polysaccharide extracted from fruit bodies of Grifola frondosa (maitake) showed an antitumor effect against mouse syngeneic tumors and acted to potentiate cellular functions and at the same time to prevent a decrease of immune functions of the tumor-bearing host.
Activity of Maitake D‐fraction to Inhibit Carcinogenesis and Metastasis
  • H. Nanba
  • Medicine
    Annals of the New York Academy of Sciences
  • 1995
TLDR
Maitake mushroom (Grijola frondosa) has the strongest antitumor activity in tumor growth inhibition both when administered orally and intraperit0neal1y.
Mushrooms, tumors, and immunity.
TLDR
The antitumor mechanisms of several species of whole mushrooms as well as of polysaccharides isolated from Lentinus edodes, Schizophyllum commune, Grifola frondosa, and Sclerotinia sclerotiorum are mediated largely by T cells and macrophages, and the means by which they modulate the immune system and potentially exert tumor-inhibitory effects are reviewed.
ANTITUMOR EFFECT OF ORALLY ADMINISTERED EXTRACTS FROM FRUIT BODY OF GRIFOLA FRONDOSA (MAITAKE)
We conducted a footpad swelling test to clarify wither a delayed type hypersensitivity (DTH) reaction against tumor antigen is potentiated by oral administration of D fraction extracted and purified
Anti-diabetic activity present in the fruit body of Grifola frondosa (Maitake). I.
TLDR
The fruit body of Grifola frondosa (maitake), Basidiomycetes was confirmed to contain substances with anti-diabetic activity and results suggest that the anti-Diabetic activity was present not only in the ES-fraction consisting of lipid but also in the X-fractions of peptidoglycan.
Effect of a polysaccharide fraction from Grifola frondosa on immune response in mice.
TLDR
GF-1 induced resistance against Sarcoma 180 in ICR mice which had completely regressed from the tumor by the effect of GF-1, and enhanced the antigen specific antibody response and carbon clearance activity.
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