Maintenance versus Manipulation of Information Held in Working Memory: An Event-Related fMRI Study

@article{DEsposito1999MaintenanceVM,
  title={Maintenance versus Manipulation of Information Held in Working Memory: An Event-Related fMRI Study},
  author={Mark D’Esposito and Bradley R. Postle and Dana Ballard and J Lease},
  journal={Brain and Cognition},
  year={1999},
  volume={41},
  pages={66-86}
}
One model of the functional organization of lateral prefrontal cortex (PFC) in primates posits that this region is organized in a dorsal/ventral fashion subserving spatial and object working memory, respectively. Alternatively, it has been proposed that a dorsal/ventral subdivision of lateral PFC instead reflects the type of processing performed upon information held in working memory. We tested this hypothesis using an event-related fMRI method that can discriminate among functional changes… 
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