Maintenance treatment with antipsychotic drugs for schizophrenia.

@article{Ceraso2020MaintenanceTW,
  title={Maintenance treatment with antipsychotic drugs for schizophrenia.},
  author={Anna Ceraso and Jessie Jingxia Lin and Johannes Schneider-Thoma and Spyridon Siafis and Magdolna Tardy and Katja Komossa and Stephan Heres and Werner Kissling and John Manley Iii Davis and Stefan Leucht},
  journal={The Cochrane database of systematic reviews},
  year={2020},
  volume={8},
  pages={
          CD008016
        }
}
  • A. Ceraso, J. Lin, S. Leucht
  • Published 11 August 2020
  • Medicine, Psychology
  • The Cochrane database of systematic reviews
BACKGROUND The symptoms and signs of schizophrenia have been linked to high levels of dopamine in specific areas of the brain (limbic system). Antipsychotic drugs block the transmission of dopamine in the brain and reduce the acute symptoms of the disorder. An original version of the current review, published in 2012, examined whether antipsychotic drugs are also effective for relapse prevention. This is the updated version of the aforesaid review. OBJECTIVES To review the effects of… 
A Complex Combination Therapy for a Complex Disease–Neuroimaging Evidence for the Effect of Music Therapy in Schizophrenia
TLDR
This review is to present the reader with a more detailed and science-based account of the beneficial effect of music therapy on the general wellbeing of patients diagnosed with schizophrenia and will focus mainly on the evidence provided by modern neuroimaging research.
Relapse prevention in schizophrenia: expectations and reality
  • M. Jarema
  • Medicine, Psychology
    Pharmacotherapy in Psychiatry and Neurology
  • 2021
TLDR
The review revealed that both pharmacological and non-pharmacological methods of treatment may be useful in the clinical improvement of schizophrenia.
A Systematic Review of Non-pharmacological Strategies to Reduce the Risk of Violence in Patients With Schizophrenia Spectrum Disorders in Forensic Settings
TLDR
It is difficult to draw firm conclusions about the effectiveness of non-pharmacological interventions to reduce the risk of violence in patents with SSD in forensic psychiatry settings due to the heterogeneity of the study designs and outcome measures.
The Scope of Metacognitive Therapy in the Treatment of Psychiatric Disorders
TLDR
This comprehensive narrative review describes the various psychiatric illnesses in which MCT has been used, the advantages of MCT, and the limitations of the MCT research, and proposes some solutions to systematically examine its place in psychiatry.
Dopamine adjusts the circadian gene expression of Per2 and Per3 in human dermal fibroblasts from ADHD patients
TLDR
The results lead to the suggestion that dopamine may improve the sleep quality as well as ADHD symptoms by adjustment of the circadian gene expression, especially for Per2 and Per3 .

References

SHOWING 1-10 OF 424 REFERENCES
Maintenance treatment with antipsychotic drugs for schizophrenia.
TLDR
The efficacy of antipsychotic drugs for maintenance treatment in schizophrenia was clear and the results of the primary outcome were robust in a number of subgroup, meta-regression and analyses.
Cessation of medication for people with schizophrenia already stable on chlorpromazine.
TLDR
This review confirms clinical experience and quantifies the risks of stopping chlorpromazine medication for a group of people with schizophrenia who are stable on this drug.
Olanzapine for schizophrenia.
TLDR
There is little to choose between the atypical antipsychotic drugs, although olanzapine may cause fewer extrapyramidal adverse effects than other drugs in this category, and results between three to 12 months suggest a clinically important average gain of four kilograms for people given olanZapine.
Long-term antipsychotic treatment in schizophrenia: systematic review and network meta-analysis of randomised controlled trials
TLDR
Except for apparent superiority of olanzapine and fluphenazine decanoate over chlorpromazine, most agents showed intermediate efficacy for relapse prevention and differences among them were minor.
T54. TAILOR – TAPERED DISCONTINUATION VERSUS MAINTENANCE THERAPY OF ANTIPSYCHOTIC MEDICATION IN PATIENTS WITH NEWLY DIAGNOSED SCHIZOPHRENIA SPECTRUM DISORDERS IN REMISSION OF PSYCHOTIC SYMPTOMS
TLDR
The TAILOR trial will contribute to knowledge about the effect of tapering/discontinuation of antipsychotic medication in early phases of schizophrenia spectrum disorders and hopefully the results may guide future clinical treatment regimens of antippsychotic medication.
Clozapine versus typical neuroleptic medication for schizophrenia.
TLDR
Clozapine treatment was more acceptable in long-term treatment than conventional antipsychotic drugs but did not differ from acceptability of high-potency neuroleptics such as haloperidol in terms of clinical improvement.
Cognitive Effects of MIN-101 in Patients With Schizophrenia and Negative Symptoms: Results From a Randomized Controlled Trial.
TLDR
Results suggest a possible benefit of MIN-101 on cognitive performance in individuals with schizophrenia with stable positive symptoms and concurrent clinically significant negative symptoms.
S227. A PROPOSED ALTERNATIVE BETWEEN DISCONTINUATION AND MAINTENANCE OF ANTIPSYCHOTICS: A GUIDED DOSE REDUCTION TRIAL FOR PATIENTS WITH REMITTED PSYCHOSIS
TLDR
Outpatients with schizophrenia-related psychotic disorders under remitted states are recruited and randomized into guided dose reduction group and maintenance treatment group and those who eligible to dose reduction yet willing to continue medication will serve as a naturalistic observation group.
...
1
2
3
4
5
...