Maintenance therapy with alternate-day prednisone improves survival in multiple myeloma patients.

@article{Berenson2002MaintenanceTW,
  title={Maintenance therapy with alternate-day prednisone improves survival in multiple myeloma patients.},
  author={James R Berenson and John J. Crowley and Thomas M. Grogan and Jeffrey Zangmeister and Adrienne D Briggs and Glenn Morris Mills and Bart Barlogie and Sydney Salmon},
  journal={Blood},
  year={2002},
  volume={99 9},
  pages={3163-8}
}
The role of maintenance therapy in multiple myeloma is controversial. Recent studies have shown an improvement in both progression-free and overall survival for patients receiving maintenance treatment with a combination of interferon and glucocorticoids, compared with interferon alone. The role of glucocorticoids alone as maintenance therapy has not been previously addressed. We compared alternate-day, oral prednisone at 2 different dose levels (10 mg versus 50 mg) for remission maintenance… CONTINUE READING

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