Maintenance of the normal rat alveolar macrophage cell population. The roles of monocyte influx and alveolar macrophage proliferation in situ.

@article{Shellito1987MaintenanceOT,
  title={Maintenance of the normal rat alveolar macrophage cell population. The roles of monocyte influx and alveolar macrophage proliferation in situ.},
  author={Judd Shellito and Claudia Esparza and Cathy Armstrong},
  journal={The American review of respiratory disease},
  year={1987},
  volume={135 1},
  pages={78-82}
}
We investigated the relative importance of monocyte influx and alveolar macrophage proliferation in maintenance of the alveolar macrophage population in normal rats. Two experimental approaches were used. To detect possible monocyte influx, we radiolabeled blood monocytes by a continuous infusion of tritiated thymidine for 7 days and assayed lavaged alveolar macrophages for radiolabel by autoradiography. Although heavily labeled monocytes occurred in the blood, no heavily labeled cells were… CONTINUE READING
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