Maintenance of the Salmonella-containing vacuole in the juxtanuclear area: a role for intermediate filaments.

@article{Guignot2008MaintenanceOT,
  title={Maintenance of the Salmonella-containing vacuole in the juxtanuclear area: a role for intermediate filaments.},
  author={Julie Guignot and Alain L. Servin},
  journal={Microbial pathogenesis},
  year={2008},
  volume={45 5-6},
  pages={415-22}
}
Until recently, intermediate filaments (IF) were thought to be only involved in resistance to physical stress and mechanical integrity of cells and tissues. Recent data indicate that IF play a much more important role in cellular physiology including organelle structure and positioning within the cell. Here, we show that Salmonella enterica serovar Typhimurium (S. typhimurium) induces in epithelial cells and macrophages the formation of an aggresome-like structure with a dramatic remodelling of… CONTINUE READING
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