Maintenance of radiation-induced intestinal fibrosis: cellular and molecular features.

@article{Haydont2007MaintenanceOR,
  title={Maintenance of radiation-induced intestinal fibrosis: cellular and molecular features.},
  author={Val{\'e}rie Haydont and Marie-Catherine Vozenin-Brotons},
  journal={World journal of gastroenterology},
  year={2007},
  volume={13 19},
  pages={
          2675-83
        }
}
Recent advances in cell and molecular radiobiology clearly showed that tissue response to radiation injury cannot be restricted to a simple cell-killing process, but depends upon continuous and integrated pathogenic processes, involving cell differentiation and crosstalk between the various cellular components of the tissue within the extracellular matrix. Thus, the prior concept of primary cell target in which a single-cell type (whatever it's epithelial or endothelial cells) dictates the… CONTINUE READING
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