Maintenance of memory CTL responses by T helper cells and CD40-CD40 ligand: antibodies provide the key.

@article{Bachmann2004MaintenanceOM,
  title={Maintenance of memory CTL responses by T helper cells and CD40-CD40 ligand: antibodies provide the key.},
  author={M F Bachmann and Lukas Hunziker and Rolf Martin Zinkernagel and Tazio Storni and Manfred Kopf},
  journal={European journal of immunology},
  year={2004},
  volume={34 2},
  pages={317-26}
}
Cytotoxic T lymphocytes (CTL) are essential for control of primary infections by many pathogens and in particular by non-cytopathic viruses. It has been proposed that long-term maintenance of CTL memory and control of lymphocytic choriomeningitis virus (LCMV) is dependent upon the presence of T helper cells and interaction of antigen-presenting cells and… CONTINUE READING