Maintenance of diversity in a hierarchical host–parasite model with balancing selection and reinfection
@article{Pokalyuk2018MaintenanceOD, title={Maintenance of diversity in a hierarchical host–parasite model with balancing selection and reinfection}, author={Cornelia Pokalyuk and A. Wakolbinger}, journal={arXiv: Probability}, year={2018} }
5 Citations
Diversity patterns in parasite populations capable for persistence and reinfection with a view towards the human cytomegalovirus
- BiologybioRxiv
- 2019
The biological relevance of both model variants with respect to the human cytomegalovirus (HCMV), an ancient herpesvirus that is carried by a substantial fraction of mankind and manages to maintain a high diversity in its coding regions, is evaluated.
Microbial populations under selection
- Biology
- 2020
A model of a host-pathogen system where the population of pathogenes experiences balancing selection, migration, and mutation, as motivated by observations of the genetic diversity of HCMV (the human cytomegalovirus) across hosts is described.
A PDE Model for Protocell Evolution and the Origin of Chromosomes via Multilevel Selection
- Biology
- 2021
The results suggest that dimerization, or the formation of a simple chromosome-like dimer replicator, can help to overcome the shadow of lower-level selection and work in concert with deterministic multilevel selection to allow for the coexistence of two genes that are complementary at the protocell-level but compete at the level of individual gene-level replication.
Long-time behavior of a PDE replicator equation for multilevel selection in group-structured populations.
- EconomicsJournal of mathematical biology
- 2022
This work considers a hyperbolic PDE model of a group-structured population, in which members within a single group compete with each other for individual-level replication; while the group also competes against other groups for group- level replication, and derives a threshold level of the relative strength of between-group competition.
Analysis of Multilevel Replicator Dynamics for General Two-Strategy Social Dilemma
- EconomicsBulletin of mathematical biology
- 2020
A game-theoretic model of multilevel selection in which individuals competebased on their payoff and groups also compete based on the average payoff of group members is considered, which finds that lower-level selection casts a long shadow and there will always be fewer cooperators than optimal at steady state.
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The biological relevance of both model variants with respect to the human cytomegalovirus (HCMV), an ancient herpesvirus that is carried by a substantial fraction of mankind and manages to maintain a high diversity in its coding regions, is evaluated.
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