Maintenance of dendritic spine morphology by partitioning-defective 1b through regulation of microtubule growth.

@article{Hayashi2011MaintenanceOD,
  title={Maintenance of dendritic spine morphology by partitioning-defective 1b through regulation of microtubule growth.},
  author={Kenji Hayashi and Atsushi Suzuki and Syu-ichi Hirai and Yasuyuki Kurihara and Casper C Hoogenraad and Shigeo Ohno},
  journal={The Journal of neuroscience : the official journal of the Society for Neuroscience},
  year={2011},
  volume={31 34},
  pages={12094-103}
}
Dendritic spines are postsynaptic structures that receive excitatory synaptic input from presynaptic terminals. Actin and its regulatory proteins play a central role in morphogenesis of dendritic spines. In addition, recent studies have revealed that microtubules are indispensable for the maintenance of mature dendritic spine morphology by stochastically invading dendritic spines and regulating dendritic localization of p140Cap, which is required for actin reorganization. However, the… CONTINUE READING
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