Maintenance of blastemal proliferation by functionally diverse epidermis in regenerating zebrafish fins.

@article{Lee2009MaintenanceOB,
  title={Maintenance of blastemal proliferation by functionally diverse epidermis in regenerating zebrafish fins.},
  author={Yoonsung Lee and Danyal Hami and Sarah J De Val and Birgit Kagermeier-Schenk and Airon A. Wills and Brian L Black and Gilbert Weidinger and Kenneth D Poss},
  journal={Developmental biology},
  year={2009},
  volume={331 2},
  pages={270-80}
}
Appendage regeneration in salamanders and fish occurs through formation and maintenance of a mass of progenitor tissue called the blastema. A dedicated epidermis overlays the blastema and is required for its proliferation and patterning, yet this interaction is poorly understood. Here, we identified molecularly and functionally distinct compartments within the basal epidermal layer during zebrafish fin regeneration. Proximal epidermal subtypes express the transcription factor lef1 and the… CONTINUE READING

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